Therapeutic drug monitoring (TDM) of atazanavir in pregnancy

Therapeutic drug monitoring (TDM) of atazanavir in pregnancy

Methods In this prospective, open labelled study, pregnant HIVpositive women received ATV/r as part of their routine pre-natal care. Demographic and clinical data were collected, and ATV plasma concentrations [ATV] were determined in the first (T1) and/or second (T2) and/or third (T3) trimester using HPLC-MS/MS (LLQ = 0.05 μg/mL). Postpartum (PP) sampling was performed where applicable. Antepar...

PT705. Therapeutic Drug Monitoring (TDM) in maternal serum, amniotic fluid and umbilical cord blood during pregnancy and delivery

s | 57 PT705 Therapeutic Drug Monitoring (TDM) in maternal serum, amniotic fluid and umbilical cord blood during pregnancy and delivery 1Michael Paulzen, 1Sarah Lammertz, 1Tanja Veselinovic, 2Tamme Goecke, 3Christoph Hiemke and 1Gerhard Gründer 1Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, and JARA—Translational Brain Medicine, Germany; 2Department of Gyna...

Potential of Surface Enhanced Raman Spectroscopy (SERS) in Therapeutic Drug Monitoring (TDM). A Critical Review

Surface-Enhanced Raman Spectroscopy (SERS) is a label-free technique that enables quick monitoring of substances at low concentrations in biological matrices. These advantages make it an attractive tool for the development of point-of-care tests suitable for Therapeutic Drug Monitoring (TDM) of drugs with a narrow therapeutic window, such as chemotherapeutic drugs, immunosuppressants, and vario...

Evaluation of VACUETTE Serum Gel Tubes for Therapeutic Drug Monitoring (TDM) in Serum

204Voriconazole Restriction in Addition to Therapeutic Drug Monitoring (TDM) Protocol Results in Optimized Dosing

204. Voriconazole Restriction in Addition to Therapeutic Drug Monitoring (TDM) Protocol Results in Optimized Dosing Natasha Pettit, PharmD; Zhe Han, PharmD; Mildred Vicente, PharmD; Emily Landon, MD; Jennifer Pisano, MD; Allison H. Bartlett, MD, MS; Pharmacy Services, University of Chicago Medicine, Chicago, IL; Pharmacy Services, University of Chicago Medicine, Chicago, IL; Infectious Diseases...